Stephen Z. Fadem, M. D.

1. Overview
2. QOL and Morbidity
QOL = energy
anemia
heart failure
Morbidity - vascular events
peripheral vascular
skin ulceration
target organs - heart, brain eyes, kidneys
3. Pathophysiology
Hypertension - tension on tissues - induces fibrocytes - wall thickens
Calcium - Calcification matrix - induces osteoblasts - wall hardens
Sugar - polymerization (AGES) - increased matrix
Inflammation + Cholesterol - macrophage - foam cell - atherosclerotic plaque

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Adding spice to Powerpoint
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Newsdesk
Keeping track of information
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Publishing and storing on the web
Paperless office
Wireless world
History and physicals without pencils